There are two kinds of people, those who do the work and those who take the credit. Try to be in the first group; there is less competition there.
– Indira Gandhi, The most dynamic woman of the twentieth century
Don’t be a know-it-all; be a learn-it-all.
– Satya Nadella, CEO, Microsoft
Principal Investigators
- Butler University
- Distinguished Faculty, 2023
- Professor, 2015 – present
- Associate Professor (tenured), 2004 – 15
- Department Chair, 2004-09
- Director of Graduate Program, 2004-18
- Indiana University, School of Medicine
- Adjunct Professor, Dept of Radiology & Imaging Sciences, 2019-2023
- Idaho State University
- Associate Professor (tenured 2003), 1998-2004
- Nova Southeastern University
- Assistant Professor, 1993-98
- Memorial University of Newfoundland, Canada
- Assistant Professor, 1991-93
- University of Queensland, Australia
- UQ PostDoctoral Fellow, 1990-91
- Butler University
- Professor, 2018 – present
- Associate Professor, 2005-2018 (tenured 2012)
- Research Associate Professor, 2004-05
- Idaho State University
- Assistant Professor, 1998-2004
- Nova Southeastern University
- Adjunct Assistant Professor, 1997-98
- Eckerd Drug Corporation (Rite Aid), Plantation, FL
- Staff Pharmacist, 1995-98
- SmithKline Beecham Pharmaceuticals (Glaxo SmithKline), King of Prussia, PA
- Graduate Scholar and Research Assistant, 1993-95
Collaborators
Mark R. Kelley, PhD, Betty and Earl Herr Professor of Pediatric Oncology Research, Indiana University School of Medicine, Indianapolis, IN
Michael C. Veronesi, MD, PhD, Associate Professor of Neuroradiology, University of Wisconsin, School of Medicine and Public Health, Madison, WI
Lab alumni – Graduate students and postdocs
Name | Role | Research Project | Current affiliation |
---|---|---|---|
Dr. Sarat Chattaraj | Postdoctoral Fellow | Oral delivery of microparticulate vaccines | Senior Principal Scientist at Viatris (Mylan Pharmaceuticals), Morgantown, WV |
Dr. Prabhakar Reddy | Postdoctoral Fellow – funded by NIH-NIDA 2005-06 | Mucoadhesive buprenorphine for opioid addiction therapy – funded by NIDA | Principal, University College of Pharmaceutical Sciences, Palamuru University, Telangana, India |
Dr. Vijay Sutariya | Postdoctoral Fellow – funded by NIH-NIGMS 2007-08 | Lymphatic targeted tamoxifen for breast cancer therapy | Associate Professor, College of Pharmacy, University of South Florida, USA |
Ms. Kanako Somatsu | MS graduate, 2007 | Liposomal delivery of siRNA for silencing of the presenilin-1 gene responsible for development of Alzheimer’s disease | Senior Product Manager, Boston Scientific, Tokyo, Japan |
Ms. Sharmeen Rafique | MS graduate, 2008 | Development of submicron emulsion formulations of doxorubicin and cyclosporine for reversal of multidrug resistance and cell survival studies in MES/SA-Dx5 cell lines | CEO, Laminos Laboratories Pvt. Ltd, Mumbai, India |
Dr. Sheetal DeMello, AAPS-AstraZeneca Award, 2007 | MS graduate, 2009 | Development of paclitaxel and cyclosporine A loaded PEG-PLGA nanoparticles for reversal of multidrug resistance in MES-SA/Dx5 cells | Senior Scientist at Sangamo Therapeutics, Inc., CA |
Dr. Amit Kumar | MS graduate, 2009 | Development and evaluation of thermoreversible gels for nasal drug delivery of troglitazone and insulin for Alzheimer’s disease | Lead Scientist, Bristol-Myers Squibb, NJ |
Ms. Satwati Shukla, | MS graduate, 2011 | Development of nanoparticulate formulations of the antiangiogenic drug sunitinib maleate and their Influence on cell survival in human umbilical vein endothelial cells | |
Ms. Ruchi Kapoor, AAPS – AstraZeneca Award, 2009 | MS graduate, 2011 | Influence of co-formulated submicron emulsions of vincristine and cyclosporine on Cell survival in multidrug resistant MES-SA/Dx5 cells | Director of Product @SAP, CA |
Ms. Yatri Patel, AAPS-Amgen Award, 2011 | MS graduate, 2012 | Aptamer conjugated PEG-PLGA nanoparticles for delivery of docetaxel to MUC-1 positive cancer cells | Scientist, Pfizer Inc, Andover, MA |
Dr. Jainik Panchal | MS graduate, 2013 | Preparation and characterization of sunitinib magnetoliposomes as a model for theranostic nanomedicine | Principal Scientist, Merck Inc, NJ |
Ms. Neelima Mantha, AAPS-Amgen Award, 2011 | MS graduate, 2013 | Inhibition of mutant Huntingtin protein with liposomal siRNA in inducible PC-12 Cells | Senior Research Associate, Genentech-Roche, CA |
Mr. Shounak Bose | MS graduate, 2014 | Ocular Formulation of a Poorly Soluble New Chemical Entity for the Treatment of Age-Related Macular Degeneration | CEO, Indo-German Pharmaceuticals, India |
Mr. Rameej Kagdi | MS graduate, 2014 | Knockdown of Survivin Protein Expression Using Liposomal siRNA | Senior Scientist at Pfizer, Chicago, IL |
Ms. Puja Kanvinde | MS graduate, 2015 | Design of targeted iRGD peptide modified PLGA nanoparticles loaded with docetaxel and their effect on MDA-MB-231 breast cancer cells | Scientist, Study Coordination at Worldwide Clinical Trials, Austin, TX |
Dr. Sanika Rege | MS graduate, 2016 | Enhanced cytotoxicity via down-regulation of Survivin expression in MCF-7 and HeLa cells by PLGA-siRNA nanoparticles | Scientist, OPEN Health HEOR & Market Access |
Dr. Raj Kammari | MS graduate, 2017 | Co-delivery of Paclitaxel and Survivin siRNA using PLGA Nanoparticles Conjugated with iRGD Peptide | Scientist, Alexion Biopharm (Astra-Zeneca), CT |
Ms. Nikeeta Kheradia | MS graduate, 2017 | Lipid Nanoemulsion of Curcuminoid Enhances Cytotoxicity and Apoptosis in HeLa cells | R&D Scientist, Verdure Sciences, IN |
Dr. Nairrita Majumdar | MS graduate, 2018 | Enhanced Cytotoxicity and Apoptosis of Triple Negative MDA-MB-231 Cells with Docetaxel Loaded and Hyaluronic Acid Conjugated Polylactide-co-glycolide-Polyethylene Glycol Nanoparticles, with or without Co-administered iRGD Peptide | Postdoc fellow, UPMC, Pittsburgh, PA |
Ms. Rukmini Ladi | MS graduate, 2019 | Self-assembling Modified β-cyclodextrin Conjugated Nanoparticles and Liposomal siRNA Efficiently Knockdown the Mutant Huntingtin Gene in a Modified PC-12 Cell Line | External Collaborations Manager, Cell Therapy & Gene Therapy, Sartorius Stedim Biotech |
Ms. Tanvi Gandhi | MS graduate, 2019 | Smart Therapy: Co-administration of Cisplatin with CCND1 siRNA Loaded Liposomes for the Treatment of Mantle Cell Lymphoma (Co-Advisor: Dr. Masamha) | Associate Consultant Scientist, Eli Lilly & Co, IN |
Ms. Nayela Chowdhury AAPS Best Poster Awardee | MS graduate, 2019 | Formulation studies on paclitaxel nanomicelles and comparative evaluation of efficacy in 2D and 3D culture models of triple negative breast cancer cells | PhD candidate, Indiana University School of Medicine, IN |
Mr. Mohammad Ramadan, Fulbright Scholar from Egypt | MS graduate, 2020 | Low-temperature, Stress-free, Scalable Production of Docetaxel Folate-targeted Liposomes and their Physicochemical Evaluation | Production supervisor at Gypto Pharma, Egypt |
Mr. Victor Anguiano-Rosales | MS graduate, 2023 | Development of a nanoemulsion delivery system for nose-to-brain delivery of aripiprazole | Senior Associate Scientist R&D, Eli Lilly & Co, IN |
Mr. Madhu Surapaneni | MS graduate, 2004 | Development of a mucoadhesive formulation of pentoxifylline | Director, Business Operations, Pfizer, NY Previously: Bristol-Myers |
Ms. Swathi Pinnamaneni | MS graduate, 2002 | Nanoemulsion delivery system for tamoxifen | Principal Scientist, PTC Therapeutics, NJ Previously: Bristol-Myers |
Lab alumni – Undergraduate students
Name | Role | Research Project | Current affiliation |
---|---|---|---|
Ms. Hannah Beaven | BS/BE Biomedical Engineering, 2024 | IU-UROP Project: Characterization of particle disposition following intranasal inoculation with a 3D-printed device | MD student at Indiana University School of Medicine |
Dr. Ryan Dimmitt | PharmD, 2017, Cum Laude | Comparative study on the efficacy of cell-penetrating peptides, iRGD and HR9, in promoting docetaxel induced cytotoxicity in breast cancer cells | |
Dr. Katie Cich AACP-Walmart Scholar | PharmD, 2012, Summa Cum Laude | Clinical Pharmacist, Orlando VA, FL | |
Dr. Samreen Khatri AFPE Gateway and Pfizer Scholarship Award | PharmD, 2008, Cum Laude | Effect of methotrexate conjugated PAMAM dendrimers on the viability of MES-SA uterine cancer cells | Staff pharmacist, Richard L. Roudebush VA Medical Center, IN |
Dr. Brenda Greenen | PharmD, 2008, Cum Laude | In Vitro Dissolution of Buprenorphine Sublingual Tablets Using a Novel Flow-Through Apparatus | |
Dr. Amelia Brandt | PharmD, 2022 | Exosome: A biogenic Nanovesicle for Anticancer Drug Delivery | |